Home  |  Research  |  People  |  Publications  |  Contact

Yu Laboratory

Welcome to the Yu laboratory @USF!

Lab News

August 23, 2021: The Yu lab is extremely excited to welcome Sarah Halabi as a Ph.D. student! #Yu Lab Milestone#

April 30, 2021:
Our research paper "Spatial regulation of Protein A in Staphylococcus aureus" was accepted for publication in Mol Microbiol. Congratulations Ran, Mac, and Sal!

April 11, 2021: Salvatore Scaffidi wins the poster award for outstanding quality of research and presentation at the 2021 USF Graduate Student Research Symposium. Congratulations Sal!

March 9, 2021: Our protocol paper "Tracking the subcellular localization of surface proteins in Staphylococcus aureus by immunofluorescence microscopy" was accepted for publication in Bio-Protocol. Congratulations Sal and Mac!

January, 2021:
The Yu lab is extremely excited to welcome Salvatore Scaffidi as the first Master's student! #Yu Lab Milestone#

March, 2020:
We are extremely excited to welcome an outstanding student, Mac Shebes, to be the first Ph.D. student of the Yu Lab! #Yu Lab Milestone#

The Yu lab at the University of South Florida kicked off in January of 2019. As a microbiology laboratory, the overall goals of the Yu lab are to:
  1. grow bacteria in the lab: We are keen on exploring and discovering the fascinating biological features of bacterial life;
  2. "grow" young scientists in the lab: We are enthusiastic about training and preparing young students for professional careers; 
  3. have fun doing 1. and 2.!
To achieve our goals, we carry out cutting-edge research projects and provide rigorous training. Our lab studies protein secretion in Staphylococcus aureus. S. aureus is one of the most important human pathogens, which is able to cause various infections, ranging from skin and soft tissue infections, pneumonia, endocarditis, osteomyelitis to life-threatening sepsis. To be such a harmful (yet successful) pathogen, S. aureus produces and secretes an arsenal of virulence factors. Most of these virulence factors are either secreted or cell wall-anchored surface proteins. Our lab studies the secretion of some of the most important proteins in S. aureus. We use a variety of experimental approaches such as genetics, biochemistry and bacterial cell biology methods to address the fundamental questions of how proteins are produced, secreted and how these are coordinated with bacterial growth and cell division.

                  trafficking of YSIRK/G-S proteins in S aureus

2019 Wenqi Yu, Rocky D. Bull and USF