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Yu Laboratory

Welcome to the Yu laboratory @USF!

The Yu lab at the University of South Florida kicked off in January of 2019. As a microbiology laboratory, the overall goals of the Yu lab are to:
  1. grow bacteria in the lab: We are keen on exploring and discovering the fascinating biological features of bacterial life;
  2. "grow" young scientists in the lab: We are enthusiastic about training and preparing young students for professional careers; 
  3. have fun doing 1. and 2.!
To achieve our goals, we carry out cutting-edge research projects and provide rigorous training. Our lab studies protein secretion in Staphylococcus aureus. S. aureus is one of the most important human pathogens, which is able to cause various infections, ranging from skin and soft tissue infections, pneumonia, endocarditis, osteomyelitis to life-threatening sepsis. To be such a harmful (yet successful) pathogen, S. aureus produces and secretes an arsenal of virulence factors. Most of these virulence factors are either secreted or cell wall-anchored surface proteins. Our lab studies the secretion of some of the most important proteins in S. aureus. We use a variety of experimental approaches such as genetics, biochemistry and bacterial cell biology methods to address the fundamental questions of how proteins are produced, secreted and how these are coordinated with bacterial growth and cell division.

Septal trafficking of YSIRK/G-S proteins in S aureus

2019 Wenqi Yu, Rocky D. Bull and USF