ß-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) is essential for bacterial fatty acid synthesis (Chiou-Yan Lai and John E. Cronan. J. Bio. Chem. 278(51), 51494-51503, 2003).
X-ray crystallographic structure of FabH dimer: PDB 1HN9, one monomer with surface rendition and one monomer with cartoon rendition. Right image is tilted 90 degrees toward viewer from left image.
X-ray crystallographic structure of FabH monomer with coenzyme A: PDB 1HND, monomer is in cartoon rendition with ligand bound with cyan-colored carbons.
Close-up of FabH active site with coenzyme A bound; interacting residues are rendered with surface and mesh.
Close-up of FabH active site with coenzyme A bound: left image: mesh rendering, right image: stick rendering